cordbloodipscells.com
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Cord Blood Induced Pluripotent Stem Cells Enhancing Therapeutic Applicability Of Cord Blood Cells And Banking Through iPS Cells Home Cord Blood Cells Regenerative Medicine Privacy Policy Cord Blood Cells (CBCs) General Hereditary Disease iPS Cells Whole Genome Sequencing Comments Posts Hereditary disease An inherited disease or genetic disorder is an illness caused by mutations or abnormalities in genes or chromosomes. In general, diseases are due in part to genetic disorders or caused by environmental factors, or both. Most disorders are quite rare and affect one person in every several thousands or millions. Some types of recessive and others are dominant gene disorders. A single gene disorder is the result of a single mutated gene. There are estimated to be over 4000 human diseases caused by single gene defects. Single gene disorders can be passed on to subsequent generations in several ways. Be the first to comment - What do you think? Posted by Ips Cell - October 8, 2010 at 10:29 pm Categories: Hereditary Disease Tags: genetic disorder, hereditary disease, inherited disease Perspectives In Modern Regenerative Medicine With the advent of whole genome sequencing and cellular reprogramming techniques current research breakthroughs holds great promise for personalizing regenerative medicine. Nowdays, the possibility to obtain customized induced pluripotent stem cells as well as full genome sequencing data for each and every person is getting closer to a reality. In this site we aim at delivering comprehensive information and updates on the several techniques involved in making personalized medicine a reality. Keep tuned!! Be the first to comment - What do you think? Posted by Ips Cell - October 7, 2010 at 7:18 pm Categories: General Tags: Induced Pluripotent Stem Cells Induced pluripotent stem cells, commonly abbreviated as iPS cells or iPSCs are a type of pluripotent stem cell synthetically derived from an adult somatic cell by heavy overexpression of a specific set of genes, typically transcription factors. The biological material used to derive iPS cells includes a wide range of tissues such as hair keratinocytes, skin fibroblasts, adipocytes from liposuction leftovers or blood cells. Cord blood cells represent an ideal cellular type for iPS cells derivation as their genome is healthier and most vigorous compared to any other somatic cell that underwent genetic injuries derived from normal cell replication errors and metabolic derived lesions. Depending on the methods used, reprogramming of adult cells to obtain iPSCs may pose significant risks that could limit its use in humans. For example, viruses are used to genomically alter the cells, heavy overexpression of cancer-causing genes or oncogenes, etc. Therefore, methods for iPS cells derivation are continuously being improved, covering from viral-integrative methods (lenti or retrovirus, plasmid or transposons), non integrative methods (episomal plasmids or viruses such adenoviru
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