PROLOTHERAPY & PERINEURAL INJECTION TREATMENT AND RESEARCH: DR REEVESGEN INFOProlo/PIT: Brief SummaryComparing Prolo and PITProlotherapy Q & ARESEARCHBasic Science Dextrose>AnalgesiaChondrogenesisTendon injection safeThickens lIgamentDextrose RCTs>Achilles TendinopathyHand OsteoarthritisKnee OsteoarthritisLateral EpicondylosisLow Back/Sacroiliac PainOsgood-Schlatter DiseasePlantar FasciosisRotator Cuff TendinopathyTemporomandibular DysfunctionDextrose Non RCTs>ACL LaxityGroin PainPatellar TendinosisShin SplintsPIT ResearchFINDING RESEARCHTRAINING IN PROLO/PITPATIENTSPRP UseStem Cell UseNew Patient Intake FormsWhat to expect in more detailDirections to Office
Fiinding a Doctor
HOPE
Dextrose Prolotherapy Metaanalyses
Prolotherapy (Regenerative Injection) and Perineural Injection Treatment (PIT): Hope for Pain Sufferers and Summary, Research, and Training for Pain Sufferers and Physicians
Author: K. Dean Reeves, M.D.(curriculum vitae below)
​General Focus of this Site:  This site specifically focuses on summary explanations for non-medical professionals (This page), research summaries for non-medical  readers and medical professionals (Research tab above), and training opportunities for physicians (Training tab above). Prospective patients can click on Patients or Hope tabs. Information about sedation prolotherapy or stem cell, PRP or ozone use are found under the Patients tab. ​  ​
Introductory Information/Overview For those who have suffered from chronic pain and found only temporary benefit from other treatments, Prolotherapy (injection to repair or regenerate ligament, tendon or cartilage) and Perineural injection treatment (PIT) (injection to restore normal function in nerves that cause pain and degeneration) are options to directly treat common underlying causes of chronic pain. I suggest that all first-time visitors to this site click on all three of the tabs seen above. It is worth noting that the evidence-basis for dextrose prolotherapy, as determined appropriately by the number of areas with level B or higher evidence of efficacy in multiple treatment areas, is more than any other injection method used for pain.  Physicians who do not agree are encouraged to become current in the medical literature in this area, beginning with the many meta-analyses that have been published. Many different specialty types use Prolotherapy and PIT (see the link below) and a realistic estimate is that it will be considered part of the essential skill set for physicians who purport to treat chronic pain by the year 2030, paricularly given the limited effectiveness of other approaches and the current opiod crisis.
Prolo/PIT: BriEF SUMMARY
COMPARING PROLO AND PIT
PROLOTHERAPY Q & A
Our most recent team publication, which appeared in Mayo Clinic Proceedings (May 2019)
Louw WF, Burrils F, Reeves KD, Cheng AL, Rabago D. Treatment of temporomandibular dysfunction with dextrose prolotherapy: A randomized controlled trial with long term