Cancer Research LabLet us start from here, away from cancer. Cancer Knowledge, give you more and more comprehensive cancer information; cancer prevention, let us start from here; cancer treatment, newer, better treatment for cancer patients regain health.High-dose chemo doesn’t improve survival in metastatic breast cancerCategories: Breast CancerHigh-dose chemotherapy with autologous stem-cell transplantation does not improve overall survival when used as consolidation therapy after response to induction therapy in women with metastatic breast cancer, Canadian researchers report.One small controlled trial has suggested there are improvements in overall survival after two courses of high-dose chemotherapy supported by autologous stem-cell transplantation, compared with standard-dose chemotherapy, the authors explain in the January 1st issue of the Journal of Clinical Oncology.More »Comorbidity reduces benefits of androgen suppression in prostate cancerCategories: Prostate CancerThe addition of androgen suppression therapy to radiation therapy for treatment of prostate cancer fails to improve survival among men with serious co-existing illness, according to a study in the Journal of the American Medical Association for January 23.Recent evidence suggests that androgen suppression therapy increases the risk of cardiovascular events in men of advanced age, lead author Dr. Anthony V. D’Amico of Brigham and Women’s Hospital in Boston and his associates note.More »Statins don’t appear to be linked with breast cancer riskCategories: Breast CancerStatin use is not associated with an increased or decreased risk of breast cancer, according to a population-based, case-control study published in the January 1st issue of Cancer.“Findings that statins inhibited the proliferation of breast cancer cells in vitro and in rodents have raised interest in whether the use of statins might decrease a woman’s risk of developing breast cancer,” Dr. Gaia Pocobelli, of the University of Washington, Seattle, and colleagues write. Conversely, other studies in which rodents were exposed to high doses of statins showed increases in several types of cancer.More »Soft-tissue sarcoma outcomes vary widely by race, ethnicityCategories: Cancer TreatmentThe treatment and survival of adults with soft-tissue sarcoma of the extremities varies widely by race and ethnicity. Compared with whites, the disease-specific mortality rates are significantly higher in blacks and significantly lower in Asians, according to authors of a paper in the March 1st issue of Cancer.To examine the effects of race and ethnicity on tumor characteristics and outcomes, Dr. Steve R. Martinez, of University of California at Davis Cancer Center in Sacramento, and colleagues used the Surveillance, Epidemiology, and End Results (SEER) database to identify 6406 patients with extremity soft-tissue sarcoma treated between 1988 and 2003. Included were 4636 white